Oligomeric structure of the multifunctional protein CAD that initiates pyrimidine biosynthesis in mammalian cells.

The first three steps in mammalian de novo pyrimidine biosynthesis are catalyzed by the multifunctional protein designated CAD. Regions of the single 240-kDa poly-peptide chain are folded into separate structural domains that have discrete functions. Previous studies suggested that CAD forms predomi...

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Hlavní autoři: Lee, L, Kelly, R E, Pastra-Landis, S C, Evans, D R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1985
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC390775/
https://ncbi.nlm.nih.gov/pubmed/2995985
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