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Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection

Mycobacterium tuberculosis (Mtb) survives under oxidatively hostile environments encountered inside host phagocytes. To protect itself from oxidative stress, Mtb produces millimolar concentrations of mycothiol (MSH), which functions as a major cytoplasmic redox buffer. Here, we introduce a novel sys...

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Detalhes bibliográficos
Main Authors: Bhaskar, Ashima, Chawla, Manbeena, Mehta, Mansi, Parikh, Pankti, Chandra, Pallavi, Bhave, Devayani, Kumar, Dhiraj, Carroll, Kate S., Singh, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907381/
https://ncbi.nlm.nih.gov/pubmed/24497832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003902
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