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Site-specific cleavage of left-handed DNA in pBR322 by lambda-tris(diphenylphenanthroline)cobalt(III).

The chiral complex tris(4,7-diphenyl-1,10-phenanthroline)cobalt(III), lambda-Co(DiP)3(3+), binds to and, with photoactivation, cleaves left-handed DNA helices, thereby providing a unique molecular probe for local DNA conformation. We have mapped the specific left-handed sites where lambda-Co(DiP)3(3...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Barton, J K, Raphael, A L
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1985
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3863105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6460
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