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Loss of Histone H3 Methylation at Lysine 4 Triggers Apoptosis in Saccharomyces cerevisiae

Monoubiquitination of histone H2B lysine 123 regulates methylation of histone H3 lysine 4 (H3K4) and 79 (H3K79) and the lack of H2B ubiquitination in Saccharomyces cerevisiae coincides with metacaspase-dependent apoptosis. Here, we discovered that loss of H3K4 methylation due to depletion of the met...

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Autors principals: Walter, David, Matter, Anja, Fahrenkrog, Birthe
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907299/
https://ncbi.nlm.nih.gov/pubmed/24497836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004095
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