Mutagenesis of avian carcinoma virus MH2: only one of two potential transforming genes (delta gag-myc) transforms fibroblasts.

Avian carcinoma virus MH2 contains two potential transforming genes, delta gag-mht and delta gag-myc. Thus, MH2 may be a model for two-gene carcinogenesis in which transformation depends on two synergistic genes. Most other directly oncogenic viruses contain single, autonomous transforming (onc) gen...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Zhou, R P, Kan, N, Papas, T, Duesberg, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3876558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6389
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