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Rethinking metabotropic glutamate receptor 5 pathological findings in psychiatric disorders: implications for the future of novel therapeutics

BACKGROUND: Pharmacological modulation of metabotropic glutamate receptor 5 (mGluR5) is of marked interest as a novel therapeutic mechanism to treat schizophrenia and major depression. However, the status of mGluR5 in the pathophysiology of these disorders remains unknown. DISCUSSION: The majority o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Newell, Kelly A, Matosin, Natalie
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907147/
https://ncbi.nlm.nih.gov/pubmed/24472577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-244X-14-23
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