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Nanoscale Drug Delivery Platforms Overcome Platinum-Based Resistance in Cancer Cells Due to Abnormal Membrane Protein Trafficking

The development of cellular resistance to platinum-based chemotherapies is often associated with reduced intracellular platinum concentrations. In some models, this reduction is due to abnormal membrane protein trafficking, resulting in reduced uptake by transporters at the cell surface. Given the c...

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Detalhes bibliográficos
Main Authors: Xue, Xue, Hall, Matthew D., Zhang, Qiang, Wang, Paul C., Gottesman, Michael M., Liang, Xing-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907077/
https://ncbi.nlm.nih.gov/pubmed/24219825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn405004f
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