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V-Phaser 2: variant inference for viral populations

BACKGROUND: Massively parallel sequencing offers the possibility of revolutionizing the study of viral populations by providing ultra deep sequencing (tens to hundreds of thousand fold coverage) of complete viral genomes. However, differentiation of true low frequency variants from sequencing errors...

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Detalhes bibliográficos
Main Authors: Yang, Xiao, Charlebois, Patrick, Macalalad, Alex, Henn, Matthew R, Zody, Michael C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907024/
https://ncbi.nlm.nih.gov/pubmed/24088188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-674
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