The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells.

The mammalian phosphatidylinositol transfer proteins (PITP) and the yeast Saccharomyces cerevisiae PITP (SEC14p) that show no sequence homology both catalyze exchange of phosphatidylinositol (PI) between membranes compartments in vitro. In HL-60 cells where the cytosolic proteins are depleted by per...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Cunningham, E, Tan, S K, Swigart, P, Hsuan, J, Bankaitis, V, Cockcroft, S
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1996
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39069/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6589
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