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Repressing the repressor: a lincRNA as a miRNA sponge in ESC self-renewal
Large intergenic non-coding (linc) RNAs constitute a new dimension of post-transcriptional gene regulation. In this issue of Developmental Cell, Wang et al. (2013) find that linc-RoR maintains human embryonic stem cell (ESC) self-renewal by functioning as a sponge to trap miR-145, thus regulating co...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906851/ https://ncbi.nlm.nih.gov/pubmed/23597480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.03.020 |
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