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Selective CB2 receptor activation ameliorates EAE by reducing Th17 differentiation and immune cell accumulation in the CNS

CB2, the cannabinoid receptor expressed primarily on hematopoietic cells and activated microglia, mediates the immunoregulatory functions of cannabinoids. The involvement of CB2 in EAE has been demonstrated by using both endogenous and exogenous ligands. We showed previously that CB2 selective agoni...

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Main Authors: Kong, Weimin, Li, Hongbo, Tuma, Ronald F., Ganea, Doina
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906668/
https://ncbi.nlm.nih.gov/pubmed/24342422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2013.11.002
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