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Prazosin, an alpha 1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat.

Prazosin, an antagonist of alpha 1-adrenergic receptors, has been found to suppress the clinical and histological expression of experimental autoimmune encephalomyelitis (EAE) in the Lewis rat. Suppression was more significant in females than in males and was a dose-dependent phenomenon. Analysis of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Brosnan, C F, Goldmuntz, E A, Cammer, W, Factor, S M, Bloom, B R, Norton, W T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390664/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.17.5915
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