Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old()

Inherited genetic variation of mitochondrial DNA (mtDNA) could account for the missing heritability of human longevity and healthy aging. Here, we show no robust association between common genetic variants of mtDNA and frailty (an “unhealthy aging” phenotype) or mortality in 700, more than 85-year-o...

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Detalhes bibliográficos
Main Authors: Collerton, Joanna, Ashok, Deepthi, Martin-Ruiz, Carmen, Pyle, Angela, Hudson, Gavin, Yadegarfar, Mohammad, Davies, Karen, Jagger, Carol, von Zglinicki, Thomas, Kirkwood, Thomas B.L., Chinnery, Patrick F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Genetic Reports Abstract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906612/
https://ncbi.nlm.nih.gov/pubmed/23639206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.04.001
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