A DNA vaccine targeting p42.3 induces protective antitumor immunity via eliciting cytotoxic CD8(+)T lymphocytes in a murine melanoma model

The p42.3 gene was recently identified and characterized as having tumor-specific and mitosis phase-dependent expression in many types of cancer. This suggested that p42.3 antigen could be used as a target for vaccines against cancers. In this study, we immunized C57BL/6 mice with a DNA vaccine enco...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Hu, Geng, Shuang, Feng, Congcong, Xie, Xiaoping, Wu, Bing, Chen, Xuan, Zou, Qiang, Wang, Shuang, Cui, Jiantao, Xing, Rui, Li, Wenmei, Lu, Youyong, Wang, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906404/
https://ncbi.nlm.nih.gov/pubmed/24051432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25013
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