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In vitro replication of duplex circular DNA containing the simian virus 40 DNA origin site.

Extracts (0.2 M NaCl) of HeLa cells support replication of DNA containing simian virus 40 (SV40) origin in the presence of SV40 large tumor (T) antigen. The reaction leads to the accumulation of high molecular weight products that represent DNA containing one parental strand and one progeny strand a...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Wobbe, C R, Dean, F, Weissbach, L, Hurwitz, J
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1985
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.17.5710
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