Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells

BACKGROUND: Hypoxia-induced genes are potential targets in cancer therapy. Responses to hypoxia have been extensively studied in vitro, however, they may differ in vivo due to the specific tumor microenvironment. In this study gene expression profiles were obtained from fresh human lung cancer tissu...

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Main Authors: Leithner, Katharina, Wohlkoenig, Christoph, Stacher, Elvira, Lindenmann, Jörg, Hofmann, Nicole A, Gallé, Birgit, Guelly, Christian, Quehenberger, Franz, Stiegler, Philipp, Smolle-Jüttner, Freyja-Maria, Philipsen, Sjaak, Popper, Helmut H, Hrzenjak, Andelko, Olschewski, Andrea, Olschewski, Horst
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905926/
https://ncbi.nlm.nih.gov/pubmed/24460801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-40
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