Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells

BACKGROUND: Hypoxia-induced genes are potential targets in cancer therapy. Responses to hypoxia have been extensively studied in vitro, however, they may differ in vivo due to the specific tumor microenvironment. In this study gene expression profiles were obtained from fresh human lung cancer tissu...

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Detalhes bibliográficos
Main Authors: Leithner, Katharina, Wohlkoenig, Christoph, Stacher, Elvira, Lindenmann, Jörg, Hofmann, Nicole A, Gallé, Birgit, Guelly, Christian, Quehenberger, Franz, Stiegler, Philipp, Smolle-Jüttner, Freyja-Maria, Philipsen, Sjaak, Popper, Helmut H, Hrzenjak, Andelko, Olschewski, Andrea, Olschewski, Horst
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905926/
https://ncbi.nlm.nih.gov/pubmed/24460801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-40
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