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Heterogeneity in type I Gaucher disease demonstrated by restriction mapping of the gene.

A cloned fragment of human glucocerebrosidase cDNA has been used as a probe to study restriction polymorphisms in the region of the gene for Gaucher disease. Variability in the size of fragments produced by digestion with the restriction endonucleases Pvu II and Kpn I was discovered. The Pvu II poly...

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Bibliografische gegevens
Hoofdauteurs: Sorge, J, Gelbart, T, West, C, Westwood, B, Beutler, E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1985
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC390585/
https://ncbi.nlm.nih.gov/pubmed/2991926
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