Hypothalamic inhibition of socio-sexual behaviour by increasing neuroestrogen synthesis

Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that inhibits gonadotropin secretion and socio-sexual behaviours. Oestrogen (neuroestrogen) synthesized in the brain from androgen by aromatase regulates male socio-sexual behaviours. Here we show that GnIH directly activates arom...

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Main Authors: Ubuka, Takayoshi, Haraguchi, Shogo, Tobari, Yasuko, Narihiro, Misato, Ishikawa, Kei, Hayashi, Takanori, Harada, Nobuhiro, Tsutsui, Kazuyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905723/
https://ncbi.nlm.nih.gov/pubmed/24430094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4061
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