Cancer-associated changes in expression of TMPRSS2-ERG, PCA3 and SPINK1 in histologically benign tissue from cancerous versus non-cancerous prostatectomy specimens

OBJECTIVE: To investigate whether mRNA expression of TMPRSS2-ERG fusion gene, a suggested prostate cancer (PCa) biomarker, was specific to cancerous lesions alone and to study the expression of SPINK1 and PCA3 mRNAs in the same cohort to also explore the proposed mutual exclusivity of TMPRSS2-ERG an...

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Main Authors: Väänänen, Riina-Minna, Lilja, Hans, Kauko, Leni, Helo, Pauliina, Kekki, Henna, Cronin, Angel M, Vickers, Andrew J, Nurmi, Martti, Alanen, Kalle, Bjartell, Anders, Pettersson, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905625/
https://ncbi.nlm.nih.gov/pubmed/24468524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2013.11.005
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