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FUNCTIONAL UNDERSTANDING OF THE DIVERSE EXON-INTRON STRUCTURES OF HUMAN GPCR GENES

The GPCR genes have a variety of exon-intron structures even though their proteins are all structurally homologous. We have examined all human GPCR genes with at least two functional protein isoforms, totaling 199, aiming to gain an understanding of what may have contributed to the large diversity o...

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Autori principali: HAMMOND, DOROTHY A., OLMAN, VICTOR, XU, YING
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905620/
https://ncbi.nlm.nih.gov/pubmed/24467758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S0219720013500194
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