Actinomycin and DNA transcription.
Recent advances in understanding how actinomycin binds to DNA have suggested its mechanism of action. Actinomycin binds to a premelted DNA conformation present within the transcriptional complex. This immobilizes the complex, interfering with the elongation of growing RNA chains. The model has a num...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390561/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2410919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.16.5328 |
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