Combination of Engineered Schwann Cell Grafts to Secrete Neurotrophin and Chondroitinase Promotes Axonal Regeneration and Locomotion after Spinal Cord Injury

Transplantation of Schwann cells (SCs) is a promising therapeutic strategy for spinal cord repair. SCs introduced into lesions support axon regeneration, but because these axons do not exit the transplant, additional approaches with SCs are needed. Here, we transplanted SCs genetically modified to s...

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Detalhes bibliográficos
Main Authors: Kanno, Haruo, Pressman, Yelena, Moody, Alison, Berg, Randall, Muir, Elizabeth M., Rogers, John H., Ozawa, Hiroshi, Itoi, Eiji, Pearse, Damien D., Bunge, Mary Bartlett
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905147/
https://ncbi.nlm.nih.gov/pubmed/24478364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2661-13.2014
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