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New Mechanisms to Explain the Effects of Added Lactose Fines on the Dispersion Performance of Adhesive Mixtures for Inhalation

Fine excipient particles or ‘fines’ have been shown to improve the dispersion performance of carrier-based formulations for dry powder inhalation. Mechanistic formulation studies have focussed mainly on explaining this positive effect. Previous studies have shown that higher drug contents may cause...

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書誌詳細
主要な著者: Grasmeijer, Floris, Lexmond, Anne J., van den Noort, Maarten, Hagedoorn, Paul, Hickey, Anthony J., Frijlink, Henderik W., de Boer, Anne H.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905031/
https://ncbi.nlm.nih.gov/pubmed/24489969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087825
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