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Artemisinin combination therapy can result in clinical failure if oral therapy is not directly observed

Intravenous artesunate therapy is the first-line therapy for severe malaria, and is highly efficacious when used in combination with an oral partner drug such as doxycycline or atovaquone-proguanil. However, treatment failure occurs routinely with artesunate monotherapy due to the very short half-li...

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Detalhes bibliográficos
Main Authors: Chan, Wilson W, Virmani, Divya, Pillai, Dylan R
Formato: Artigo
Idioma:Inglês
Publicado em: Pulsus Group Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905005/
https://ncbi.nlm.nih.gov/pubmed/24489564
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