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Broad Shifts in Gene Expression during Early Postnatal Life Are Associated with Shifts in Histone Methylation Patterns

During early postnatal life, extensive changes in gene expression occur concomitantly in multiple major organs, indicating the existence of a common core developmental genetic program. This program includes hundreds of growth-promoting genes that are downregulated with age in liver, kidney, lung, an...

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Autores principales: Lui, Julian C., Chen, Weiping, Cheung, Crystal S. F., Baron, Jeffrey
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904965/
https://ncbi.nlm.nih.gov/pubmed/24489814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086957
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