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Mycobacteria Bypass Mucosal NF-kB Signalling to Induce an Epithelial Anti-Inflammatory IL-22 and IL-10 Response

The mechanisms by which mycobacteria subvert the inflammatory defence to establish chronic infection remain an unresolved question in the pathogenesis of tuberculosis. Using primary epithelial cells, we have analysed mycobacteria induced epithelial signalling pathways from activation of TLRs to cyto...

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Detalhes bibliográficos
Main Authors: Lutay, Nataliya, Håkansson, Gisela, Alaridah, Nader, Hallgren, Oskar, Westergren-Thorsson, Gunilla, Godaly, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904915/
https://ncbi.nlm.nih.gov/pubmed/24489729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086466
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