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Astrocytes Modulate the Polarization of CD4(+) T Cells to Th1 Cells

T-cell characteristics are dynamic and influenced by multiple factors. To test whether cells and the environment in the central nervous system (CNS) can influence T-cells, we tested if culturing mouse CD4(+) T-cells on mouse primary astrocytes, compared with standard feeder cells, modified T-cell po...

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Autores principales: Beurel, Eléonore, Harrington, Laurie E., Buchser, William, Lemmon, Vance, Jope, Richard S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904883/
https://ncbi.nlm.nih.gov/pubmed/24489707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086257
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