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Structural Insights into Complexes of Glucose-Regulated Protein94 (Grp94) with Human Immunoglobulin G. Relevance for Grp94-IgG Complexes that Form In Vivo in Pathological Conditions

While the mechanism by which Grp94 displays its chaperone function with client peptides in the cell has been elucidated extensively, much less is known about the nature and properties of how Grp94 can engage binding to proteins once it is exposed on the cell surface or liberated in the extra-cellula...

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Detalhes bibliográficos
Main Authors: Pagetta, Andrea, Tramentozzi, Elisa, Tibaldi, Elena, Cendron, Laura, Zanotti, Giuseppe, Brunati, Anna Maria, Vitadello, Maurizio, Gorza, Luisa, Finotti, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904872/
https://ncbi.nlm.nih.gov/pubmed/24489700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086198
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