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EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells
BACKGROUND: Epstein-Barr Virus (EBV) latently infects ~10% of gastric carcinomas (GC). Epstein-Barr Nuclear Antigen 1 (EBNA1) is expressed in EBV-associated GC, and can bind host DNA, where it may impact cellular gene regulation. Here, we show that EBNA1 binds directly to DNA upstream of the diverge...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904692/ https://ncbi.nlm.nih.gov/pubmed/24460791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-12 |
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