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Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection

Th cells are the major effector cells in transplant rejection and can be divided into Th1, Th2, Th17, and Treg subsets. Th differentiation is controlled by transcription factor expression, which is driven by positive and negative cytokine and chemokine stimuli at the time of T cell activation. Here...

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Hlavní autoři: Shi, Guanfang, Field, David J., Ko, Kyung-ae, Ture, Sara, Srivastava, Kalyan, Levy, Scott, Kowalska, M. Anna, Poncz, Mortimer, Fowell, Deborah J., Morrell, Craig N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904624/
https://ncbi.nlm.nih.gov/pubmed/24463452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71858
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