Prenatal retinoid deficiency leads to airway hyperresponsiveness in adult mice

There is increasing evidence that vitamin A deficiency in utero correlates with abnormal airway smooth muscle (SM) function in postnatal life. The bioactive vitamin A metabolite retinoic acid (RA) is essential for formation of the lung primordium; however, little is known about the impact of early f...

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Hlavní autoři: Chen, Felicia, Marquez, Hector, Kim, Youn-Kyung, Qian, Jun, Shao, Fengzhi, Fine, Alan, Cruikshank, William W., Quadro, Loredana, Cardoso, Wellington V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904614/
https://ncbi.nlm.nih.gov/pubmed/24401276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70291
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