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Functional characterization of Upf1 targets in Schizosaccharomyces pombe

Nonsense-mediated mRNA decay (NMD) is a highly conserved mechanism of mRNA degradation. NMD eliminates mRNAs containing premature termination codons (PTCs), preventing the production of truncated proteins with possible deleterious effects. However, there is mounting evidence that NMD factors, like U...

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Detalhes bibliográficos
Main Authors: Matia-González, Ana M., Hasan, Ayesha, Moe, Gøril H., Mata, Juan, Rodríguez-Gabriel, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904585/
https://ncbi.nlm.nih.gov/pubmed/23619768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.24569
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