A Proposal for Integrated Efficacy-to-Effectiveness (E2E) Clinical Trials

We propose an “efficacy-to-effectiveness” (E2E) clinical trial design, in which an effectiveness trial would commence seamlessly upon completion of the efficacy trial. Efficacy trials use inclusion/exclusion criteria to produce relatively homogeneous samples of participants with the target condition...

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Main Authors: Selker, H P, Oye, K A, Eichler, H-G, Stockbridge, N L, Mehta, C R, Kaitin, K I, McElwee, N E, Honig, P K, Erban, J K, D'Agostino, R B
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
Ábhair:
State of the Art
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904553/
https://ncbi.nlm.nih.gov/pubmed/24060819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.177
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