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The Cancer Drug Tamoxifen: A Potential Therapeutic Treatment for Spinal Cord Injury

Tamoxifen (TMX) is a selective estrogen receptor modulator that can mimic the neuroprotective effects of estrogen but lacks its systemic adverse effects. We found that TMX (1 mg/day) significantly improved the motor recovery of partially paralyzed hind limbs of male adult rats with thoracic spinal c...

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Détails bibliographiques
Auteurs principaux: Guptarak, Jutatip, Wiktorowicz, John E., Sadygov, Rovshan G., Zivadinovic, Dragoslava, Paulucci-Holthauzen, Adriana A., Vergara, Leoncio, Nesic, Olivera
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904530/
https://ncbi.nlm.nih.gov/pubmed/24004276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2013.3108
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