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Microfluidics platform for single-shot dose-response analysis of chloride channel-modulating compounds

We previously developed cell-based kinetics assays of chloride channel modulators utilizing genetically encoded yellow fluorescent proteins. Fluorescence platereader-based high-throughput screens yielded small-molecule activators and inhibitors of the cAMP-activated chloride channel CFTR and calcium...

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Autors principals: Jin, Byung-Ju, Ko, Eun-A, Namkung, Wan, Verkman, A.S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904508/
https://ncbi.nlm.nih.gov/pubmed/23907501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3lc50821h
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