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The utility of human challenge studies in vaccine development: lessons learned from cholera

Experiments in which virulent infectious organisms are administered to healthy adult volunteers with the intent to deliberately induce infection have been practiced for centuries. Many useful applications have developed from these experiments such as the provision of evidence of microbial pathogenic...

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Autores principales: Shirley, Debbie-Ann T, McArthur, Monica A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904492/
https://ncbi.nlm.nih.gov/pubmed/24482781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/VDT.S23634
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