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Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene.

The structural gene for yeast DNA topoisomerase I (TOP1) has been cloned from two yeast genomic plasmid banks. Integration of a plasmid carrying the gene into the chromosome and subsequent genetic mapping shows that TOP1 is identical to the gene previously called MAK1. Seven top1 (mak1) mutants incl...

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Détails bibliographiques
Auteurs principaux: Thrash, C, Bankier, A T, Barrell, B G, Sternglanz, R
Format: Artigo
Langue:Inglês
Publié: 1985
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC390416/
https://ncbi.nlm.nih.gov/pubmed/2989818
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