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Characterizing the Retinoblastoma 1 locus: putative elements for Rb1 regulation by in silico analysis

Limited understanding of the Rb1 locus hinders genetic and epigenetic analyses of Retinoblastoma, a childhood cancer of the nervous systems. In this study, we used in silico tools to investigate and review putative genetic and epigenetic elements of the Rb1 gene. We report transcription start sites,...

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Main Authors: Hajjari, Mohammadreza, Khoshnevisan, Atefeh, Lemos, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904107/
https://ncbi.nlm.nih.gov/pubmed/24478791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00002
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