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Genome Recognition by MYC

MYC dimerizes with MAX to bind DNA, with a preference for the E-box consensus CACGTG and several variant motifs. In cells, MYC binds DNA preferentially within transcriptionally active promoter regions. Although several thousand promoters are bound under physiological (low MYC) conditions, these repr...

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Detalles Bibliográficos
Main Authors: Sabò, Arianna, Amati, Bruno
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904094/
https://ncbi.nlm.nih.gov/pubmed/24492846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014191
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