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Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cells.

Extracts from interferon-treated human cells show an enhanced level of a double-stranded RNA-dependent protein kinase activity that is manifested by the phosphorylation of an endogenous Mr 69,000-72,000 protein in its phosphate-saturated state. By using a highly purified protein kinase fraction from...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Laurent, A G, Krust, B, Galabru, J, Svab, J, Hovanessian, A G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390409/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3859866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.13.4341
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