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Biological activity of mRNA immobilized on nitrocellulose in NaI.

In 12.2 molal NaI and at 25 degrees C or below, mRNA bound to nitrocellulose while DNA and rRNA did not. Neither the poly(A) tract nor the cap were required for binding. The immobilized RNA could be translated, reverse transcribed, hybridized with radioactive probes, or released for further manipula...

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Détails bibliographiques
Auteurs principaux: Bresser, J, Hubbell, H R, Gillespie, D
Format: Artigo
Langue:Inglês
Publié: 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC390385/
https://ncbi.nlm.nih.gov/pubmed/6579539
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