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Covalently attached oligodeoxyribonucleotides induce RNase activity of a short peptide and modulate its base specificity
New artificial ribonucleases, conjugates of short oligodeoxyribonucleotides with peptides containing alternating arginine and leucine, were synthesized and characterized in terms of their catalytic activity and specificity of RNA cleavage. The conjugates efficiently cleave different RNAs within sing...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390365/ https://ncbi.nlm.nih.gov/pubmed/15047859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh514 |
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