Evaluation of Hyperpolarized [1-(13)C]-Pyruvate by Magnetic Resonance to Detect Ionizing Radiation Effects in Real Time

Ionizing radiation (IR) cytotoxicity is primarily mediated through reactive oxygen species (ROS). Since tumor cells neutralize ROS by utilizing reducing equivalents, we hypothesized that measurements of reducing potential using real-time hyperpolarized (HP) magnetic resonance spectroscopy (MRS) and...

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Bibliografiske detaljer
Main Authors: Sandulache, Vlad C., Chen, Yunyun, Lee, Jaehyuk, Rubinstein, Ashley, Ramirez, Marc S., Skinner, Heath D., Walker, Christopher M., Williams, Michelle D., Tailor, Ramesh, Court, Laurence E., Bankson, James A., Lai, Stephen Y.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903593/
https://ncbi.nlm.nih.gov/pubmed/24475215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087031
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