Evaluation of Hyperpolarized [1-(13)C]-Pyruvate by Magnetic Resonance to Detect Ionizing Radiation Effects in Real Time

Ionizing radiation (IR) cytotoxicity is primarily mediated through reactive oxygen species (ROS). Since tumor cells neutralize ROS by utilizing reducing equivalents, we hypothesized that measurements of reducing potential using real-time hyperpolarized (HP) magnetic resonance spectroscopy (MRS) and...

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Autors principals: Sandulache, Vlad C., Chen, Yunyun, Lee, Jaehyuk, Rubinstein, Ashley, Ramirez, Marc S., Skinner, Heath D., Walker, Christopher M., Williams, Michelle D., Tailor, Ramesh, Court, Laurence E., Bankson, James A., Lai, Stephen Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903593/
https://ncbi.nlm.nih.gov/pubmed/24475215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087031
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