Schisandra chinensis Peptidoglycan-Assisted Transmembrane Transport of Lignans Uniquely Altered the Pharmacokinetic and Pharmacodynamic Mechanisms in Human HepG2 Cell Model

Schisandra chinensis (Turz Baill) (S. chinensis) (SC) fruit is a hepatoprotective herb containing many lignans and a large amount of polysaccharides. A novel polysaccharide (called SC-2) was isolated from SC of MW 841 kDa, which exhibited a protein-to-polysaccharide ratio of 0.4089, and showed a cha...

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Detalhes bibliográficos
Main Authors: Chyau, Charng-Cherng, Ker, Yaw-Bee, Chang, Chi-Huang, Huang, Shiau-Huei, Wang, Hui-Er, Peng, Chiung-Chi, Peng, Robert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903492/
https://ncbi.nlm.nih.gov/pubmed/24475039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085165
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