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Calculating the statistical significance of physical clusters of co-regulated genes in the genome: the role of chromatin in domain-wide gene regulation

Physical clusters of co-regulated, but apparently functionally unrelated, genes are present in many genomes. Despite the important implication that the genomic environment contributes appreciably to the regulation of gene expression, no simple statistical method has been described to identify physic...

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Hlavní autoři: Chang, Cheng-Fu, Wai, Ka-Man, Patterton, Hugh G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC390345/
https://ncbi.nlm.nih.gov/pubmed/15034148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh507
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