Učitavanje...
Translational regulation of BACE-1 expression in neuronal and non-neuronal cells
As the main beta-secretase of the central nervous system, BACE-1 is a key protein in the pathogenesis of Alzheimer’s disease. Excessive expression of the protein might cause an overproduction of the neurotoxic beta-amyloid peptide. Therefore, a tight regulation of BACE-1 expression is expected in vi...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2004
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390341/ https://ncbi.nlm.nih.gov/pubmed/15034149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh348 |
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