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Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions

The sources and consequences of nongenetic variability in metastatic progression are largely unknown. To address these questions, we characterized a transcriptional regulatory network for the metastasis suppressor Raf kinase inhibitory protein (RKIP). We previously showed that the transcription fact...

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Detalhes bibliográficos
Main Authors: Lee, Jiyoung, Lee, Jinho, Farquhar, Kevin S., Yun, Jieun, Frankenberger, Casey A., Bevilacqua, Elena, Yeung, Kam, Kim, Eun-Jin, Balázsi, Gábor, Rosner, Marsha Rich
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903259/
https://ncbi.nlm.nih.gov/pubmed/24395801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304840111
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