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Polymorphisms in the CD1d promoter that regulate CD1d gene expression are associated with impaired NKT cell development()

CD1d-restricted NKT cells comprise an innate-like T cell population that exerts significant influence over early events in the developing immune response. The frequency of NKT cells is highly variable in humans and in mice, but the basis for this variability remains unclear. Here, we report a striki...

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Autores principales: Borg, Zachary D., Benoit, Patrick J., Lilley, Graham W.J., Aktan, Idil, Chant, Alan, DeVault, Victoria L., Rincon, Mercedes, Boyson, Jonathan E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903119/
https://ncbi.nlm.nih.gov/pubmed/24307737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301451
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