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Surface-Constrained 3D Reconstruction in Cryo-EM

Random spherically-constrained (RSC) reconstruction is a new form of single particle reconstruction (SPR) using cryo-EM images of membrane proteins embedded in spherical lipid vesicles to generate a 3D protein structure. The method has many advantages over conventional SPR, including a more native e...

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Autors principals: Barthel, Andrew C., Tagare, Hemant, Sigworth, Fred J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903049/
https://ncbi.nlm.nih.gov/pubmed/24477184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/ACSSC.2011.6190167
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